4-(2-Pyridinyl)phenylboronic acid pinacol ester is an organic compound with the chemical formula C16H19BO2N. It is a solid and soluble in many organic solvents. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: Colorless solid
-Melting point: about 85-87 degrees Celsius
-Molecular weight: about 277.14g/mol
-Density: about 1.1g/cm³
-May cause irritation to the eyes, skin and respiratory system, potentially low risk
Use:
- 4-(2-Pyridinyl)phenylboronic acid pinacol ester is one of the reagents commonly used in organic synthesis.
-It can be used as an intermediate of compounds and used to synthesize various heterocyclic compounds, such as pyridine, imidazole and thiophene.
-Because of its high stability, it is widely used in the fields of medicinal chemistry and materials science.
Method:
- 4-(2-Pyridinyl)phenylboronic acid pinacol ester is generally prepared by reacting phenylboronic acid with 2-bromopyridine and pinacol.
Safety Information:
-When handling this compound, care should be taken to avoid inhalation, contact with skin and eyes.
-During operation, good laboratory practices and safe operating procedures should be followed.
-If inadvertently exposed to the compound, wash the affected area immediately and seek medical help.
Please note that this is only a general introduction to 4-(2-Pyridinyl)phenylboronic acid pinacol ester. Please read the relevant safety data and literature carefully when experimenting and applying this compound.